The infection of cultured human cells with baboon endogenous virus (BEV) frequently leads to an association of viral DNA with a specific genetic locus (termed BEVI, for baboon endogenous virus infection) on chromosome 6. Restriction endonuclease digestion of DNA from BEV-infected human cells and their derived somatic cell clones frequently revealed a common cellular DNA sequence in the proximity of one of the junctions between细胞DNA和整合病毒 。我们提出 ,在染色体6上重复的短细胞DNA序列并以独特的DNA序列分离,它为在人类细胞中整合BEV的高亲和力靶标提供了一个高亲和力的靶标。
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本文概览: The infection of cultured human cells with baboon endogenous virus (BEV) frequently le...
文章不错《在人类染色体上的BEVI基因座中,狒狒内源性病毒的有针对性整合》内容很有帮助